REM Protect an app from Copernic indexing interference
"F:\Program Files\Copernic Desktop Search - Home\DesktopSearch.exe" /stop_indexing

REM do some critical work that indexing might interfere with
REM ...

"F:\Program Files\Copernic Desktop Search - Home\DesktopSearch.exe" /start_indexing

REM O&O Defrag requires you to shut down Copernic altogether, not just stop indexing, while it works.
"F:\Program Files\Copernic Desktop Search - Home\DesktopSearch.exe" /close

REM bring up the GUI so you can do searches
"F:\Program Files\Copernic Desktop Search - Home\DesktopSearch.exe" /activate

REM I could not find a reindex command. You must do that from the GUI.